Eiffel's Supercritical Fluid (SCF), or “dense gas” technologies are used to produce very small particles of therapeutic agents. The powders produced typically have very small particle size range distributions and consistent surface properties which are difficult to achieve by conventional techniques.

These outcomes are made possible because of the unique properties of SCFs, where compounds display both liquid and gas-like properties under defined conditions of temperature and pressure. A SCF can display the solvent strength of a liquid, yet permeability similar to that of a gas.

These properties can be utilised in different ways to gain fine control of particle growth from a solution or the liquid state.

This forms the basis of Eiffel’s engineering solution to the challenge of producing drug powders with physical properties that enhance their clinical and market performance.

SCF technologies can also be used for the extraction, fractionation or purification of complex chemical mixtures to yield products with little or no residual solvent.